Cell membrane lipid peroxidation
nounPronunciation: /sɛl ˈmɛmbreɪn ˈlɪpɪd pɛrɒksɪˈdeɪʃən/
The oxidative degradation of membrane phospholipids caused by free radical attack, resulting in loss of membrane integrity and cellular leakage. This process generates cytotoxic lipid peroxides and reactive aldehyde fragments that further compromise cellular function.
Plain English
Damage to cell membrane fats by harmful oxygen molecules, causing the cell to lose its protective barrier.
Etymology & History
Usage
"Malondialdehyde accumulation indicates elevated cell membrane lipid peroxidation during salinity stress in wheat roots."
Style guide notes: Use specific indicator term (e.g., 'MDA-based lipid peroxidation') when reporting quantitative data.
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Related Terms
Frequently Asked Questions
How is cell membrane lipid peroxidation measured experimentally?
Primarily through quantification of malondialdehyde (MDA) using thiobarbituric acid reactive substances assays.
What is the biological consequence of this process?
Loss of membrane semipermeability, ionic imbalance, and potential cell death if damage exceeds repair capacity.
Why Test Candidates on This?
Essential marker for assessing cellular damage severity under multiple abiotic stresses in physiological studies.
Required skill level: Senior