naloxone
Pronunciation: nal-OX-one
Opioid antagonist medication used to reverse potentially fatal opioid overdoses.
Full Definition
Naloxone is a fast-acting opioid receptor antagonist that rapidly displaces opioids from brain receptors, effectively reversing respiratory depression and other life-threatening effects of opioid overdose. Available as nasal sprays (Narcan) or auto-injectors (Evzio), naloxone can be administered by trained individuals including family members, first responders, and community members. Its effects are temporary, typically lasting 30-90 minutes, so emergency medical care is still necessary after administration. Naloxone has become a cornerstone of harm reduction strategies.
Usage
Usage note: Brand name Narcan is often used interchangeably but should be capitalized when referring to the specific product.
In Context
- "All staff members received training on proper naloxone administration techniques." — Staff training manual
- "The patient's family was provided with naloxone kits and emergency response instructions." — Discharge planning note