IGF-1
Also written as: IGF-1 — Insulin-like Growth Factor-1
Insulin-like growth factor-1, a hormone crucial for adolescent growth assessment and growth hormone evaluation.
Full Definition
Insulin-like growth factor-1 (IGF-1) is a hormone primarily produced by the liver in response to growth hormone stimulation, playing a crucial role in linear growth during adolescence. IGF-1 levels are commonly measured in adolescent endocrinology to evaluate growth disorders, as they provide a more stable indicator of growth hormone status than direct growth hormone measurement. Normal IGF-1 levels vary significantly with age, sex, and pubertal stage, requiring age-appropriate reference ranges for interpretation. Low IGF-1 levels may indicate growth hormone deficiency, while elevated levels could suggest growth hormone excess or other endocrine disorders.
Usage
Usage note: Always include hyphen and number; capitalize as shown.
In Context
- "The adolescent's IGF-1 level was below the 5th percentile, supporting a diagnosis of growth hormone deficiency." — Laboratory interpretation
- "IGF-1 monitoring during growth hormone therapy helps assess treatment efficacy and adjust dosing." — Treatment protocol