PCOS
Also written as: PCOS — polycystic ovary syndrome
Polycystic ovary syndrome, a common endocrine disorder in adolescent females characterized by irregular periods, hyperandrogenism, and metabolic abnormalities.
Full Definition
Polycystic ovary syndrome (PCOS) affects 5-10% of reproductive-age women and often manifests during adolescence with irregular menstrual cycles, acne, hirsutism, and weight gain. The disorder involves hormonal imbalances including elevated androgens and insulin resistance, leading to metabolic complications such as diabetes and cardiovascular disease. Diagnosis in adolescents requires careful consideration as normal pubertal development can mimic PCOS features. Management includes lifestyle modifications, hormonal contraceptives for cycle regulation, and metformin for metabolic components.
Usage
Usage note: PCOS is always capitalized as an acronym. Spell out polycystic ovary syndrome on first use in formal documents.
In Context
- "The 16-year-old patient met criteria for PCOS with oligomenorrhea and clinical hyperandrogenism." — Gynecologic evaluation
- "PCOS screening should include assessment of metabolic parameters and cardiovascular risk factors." — Clinical guideline