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Professional Technical In the Industry Vocabulary Test

SHBG

Also written as: SHBG — Sex hormone-binding globulin

Protein that binds and transports sex hormones in the blood.

Full Definition

Sex hormone-binding globulin is a glycoprotein that binds testosterone and estradiol, affecting their bioavailability during adolescence. SHBG levels are influenced by age, sex, body composition, and various medical conditions. In adolescent medicine, SHBG testing helps evaluate hormonal status, particularly in cases of hirsutism, irregular menses, or suspected androgen excess.

Usage

Usage note: Always spell out on first use; critical for interpreting hormone levels in adolescents.

In Context

  • "SHBG levels were elevated, suggesting reduced bioavailable testosterone." — Laboratory interpretation
  • "The clinician ordered SHBG to better understand the patient's androgen status." — Endocrine evaluation

Also known as

sex hormone-binding globulin

Don't confuse with

free testosterone total testosterone

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