thelarche
Pronunciation: thee-LAR-kee
The onset of breast development, typically the first sign of puberty in girls.
Full Definition
Thelarche refers to the initial development of breast tissue in girls, usually occurring between ages 8-13 years and representing the first visible sign of pubertal onset. Premature thelarche occurs when breast development begins before age 8 in girls, while delayed thelarche indicates absence of breast development by age 13. Clinical evaluation includes assessment of breast staging and exclusion of underlying endocrine disorders.
Usage
Usage note: Used specifically for female breast development; gynecomastia refers to male breast tissue.
In Context
- "Thelarche occurred at age 9.5 years, within the normal range for pubertal onset." — Growth and development assessment
- "Isolated premature thelarche was diagnosed after comprehensive endocrine evaluation." — Pediatric endocrinology consultation