non-ST-elevation myocardial infarction
Also written as: NSTEMI — Non-ST-Elevation Myocardial Infarction
A type of heart attack characterized by elevated cardiac biomarkers without ST-segment elevation on electrocardiogram.
Full Definition
Non-ST-elevation myocardial infarction (NSTEMI) is a form of acute coronary syndrome where myocardial necrosis occurs due to coronary artery occlusion or severe stenosis, but without the characteristic ST-segment elevation seen on electrocardiogram. Diagnosis requires elevated cardiac troponin levels along with clinical evidence of myocardial ischemia. NSTEMI typically results from subtotal occlusion of a coronary artery, often due to plaque rupture with subsequent thrombus formation. The management approach differs from STEMI, usually involving early invasive strategy rather than immediate primary percutaneous coronary intervention.
Usage
Usage note: Use hyphens in the full term; acronym NSTEMI does not require periods between letters.
In Context
- "The patient presented with NSTEMI and underwent coronary angiography within 24 hours of admission." — Hospital discharge summary
- "Risk stratification tools help determine the timing of invasive management in non-ST-elevation myocardial infarction." — Clinical practice guidelines