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leptomeningeal enhancement
Abnormal contrast enhancement of the pia and arachnoid membranes visible on contrast-enhanced MRI.
Full Definition
Leptomeningeal enhancement refers to abnormal enhancement of the leptomeninges (pia mater and arachnoid) on contrast-enhanced MRI or CT imaging. This finding suggests inflammation, infection, or malignant infiltration of these delicate membrane layers surrounding the brain and spinal cord. Common causes include meningitis, carcinomatous meningitis, sarcoidosis, and autoimmune conditions. The enhancement pattern can be focal or diffuse and may follow sulci and cisterns.
Usage
Usage note: Distinct from pachymeningeal (dural) enhancement; leptomeninges are the inner meningeal layers.
In Context
- "Post-contrast MRI demonstrated diffuse leptomeningeal enhancement throughout the cerebral sulci." — Radiology report
- "Leptomeningeal enhancement raised concern for carcinomatous meningitis." — Oncology consultation
Also known as
pial enhancement
meningeal enhancement
Don't confuse with
pachymeningeal enhancement
vascular enhancement