lithium toxicity
A dangerous condition resulting from elevated lithium levels in the blood, requiring immediate medical intervention.
Full Definition
Lithium toxicity occurs when serum lithium levels exceed therapeutic ranges, typically above 1.5 mEq/L, leading to potentially life-threatening complications. Symptoms progress from mild (nausea, tremor, confusion) to severe (seizures, coma, kidney failure). Risk factors include dehydration, drug interactions, kidney dysfunction, and dosing errors. Regular monitoring of serum lithium levels is essential for patients on lithium therapy. Treatment involves discontinuation of lithium, supportive care, and in severe cases, hemodialysis to remove excess lithium from the bloodstream.
Usage
Usage note: Always specify as 'toxicity' rather than 'poisoning' in clinical contexts.
In Context
- "The emergency department suspected lithium toxicity based on the patient's altered mental status and tremor." — Emergency medicine consultation
- "Patient education should emphasize the importance of maintaining adequate hydration to prevent lithium toxicity." — Discharge planning note