cardiac resynchronization therapy
A pacing technique using specialized devices to coordinate ventricular contractions in patients with heart failure and conduction delays.
Full Definition
Cardiac resynchronization therapy (CRT) is an advanced pacing modality designed to restore synchronized ventricular contraction in patients with heart failure and ventricular dyssynchrony. The therapy involves implanting a specialized device that paces both ventricles simultaneously through leads placed in the right ventricle and coronary sinus (for left ventricular pacing). CRT is indicated for patients with reduced ejection fraction, wide QRS complexes (typically ≥150 ms), and optimal medical therapy failure. The therapy aims to improve ventricular filling, reduce mitral regurgitation, and enhance cardiac output. CRT devices may include defibrillator capabilities (CRT-D). Success is measured by clinical improvement, echocardiographic response, and reduced hospitalizations.
Usage
Usage note: Distinguish between CRT-P (pacemaker) and CRT-D (defibrillator) devices when applicable.
In Context
- "The patient demonstrated excellent response to cardiac resynchronization therapy with improved exercise tolerance." — Heart failure clinic note
- "Cardiac resynchronization therapy optimization was performed using echocardiographic guidance." — Device clinic report