PRF
Pronunciation: P-R-F (spell out)
Also written as: PRF — Platelet-Rich Fibrin
Abbreviation for platelet-rich fibrin, a second-generation autologous blood concentrate used in aesthetic regenerative treatments.
Full Definition
PRF (platelet-rich fibrin) differs from PRP in that it undergoes a slower, lower-speed centrifugation without anticoagulants, yielding a fibrin matrix rich in platelets, leukocytes, and growth factors. In aesthetic dermatology it is used for facial rejuvenation, under-eye treatment, and hair restoration. Editors must not conflate PRF with PRP; they are related but distinct preparations with different processing protocols and clinical properties. The abbreviation PRF should be expanded on first use, and 'fibrin' must not be rendered as 'fibrin-rich plasma', which is a common drafting error.
Usage
Usage note: Expand on first use. Do not use interchangeably with PRP. The key distinguishing feature is the fibrin scaffold, absent in standard PRP preparations.
In Context
- "The injector chose PRF over PRP for the periorbital treatment owing to its slower release of growth factors." — Clinical case study
- "Ensure PRF is expanded to 'platelet-rich fibrin' at first mention; do not substitute 'platelet-rich plasma'." — Copy-editing instruction