fibromuscular dysplasia
Non-atherosclerotic vascular disease causing arterial stenosis, typically affecting renal and carotid arteries.
Full Definition
Fibromuscular dysplasia (FMD) is a non-inflammatory, non-atherosclerotic vascular disease that causes arterial stenosis, occlusion, aneurysm, or dissection. The condition most commonly affects medium-sized arteries, particularly the renal and internal carotid arteries, and predominantly occurs in women. FMD is characterized by abnormal cellular proliferation and organization within the arterial wall, creating a characteristic 'string of beads' appearance on angiography. The etiology remains unclear, though genetic and hormonal factors are suspected.
Usage
Usage note: Often abbreviated as FMD in clinical documentation.
In Context
- "The classic 'string of beads' appearance on angiography confirmed the diagnosis of fibromuscular dysplasia." — Interventional radiology report
- "Fibromuscular dysplasia should be considered in young women presenting with hypertension and renal artery stenosis." — Nephrology consultation