hemodynamically significant stenosis
Arterial narrowing that produces measurable reduction in blood flow or pressure across the lesion, typically requiring intervention.
Full Definition
Hemodynamically significant stenosis refers to arterial narrowing that creates sufficient resistance to blood flow to produce measurable physiologic changes downstream from the lesion. This significance is typically defined by specific criteria such as greater than 50% diameter reduction in major vessels, pressure gradients across the stenosis, or functional flow impairment. The determination of hemodynamic significance is crucial for treatment decisions, as it distinguishes stenoses that require intervention from those that can be managed conservatively. Assessment methods include pressure wire measurements, flow velocity ratios, and functional imaging studies.
Usage
Usage note: Distinguish from anatomical severity; hemodynamic significance requires functional assessment.
In Context
- "Pressure wire measurements confirmed hemodynamically significant stenosis of the renal artery." — Interventional cardiology report
- "Despite angiographic appearance, the lesion was not hemodynamically significant based on functional assessment." — Vascular surgery consultation