hemodynamically significant
A lesion or condition that causes measurable impairment of blood flow sufficient to affect organ perfusion or cardiac function.
Full Definition
Hemodynamically significant describes a vascular lesion, stenosis, or pathological condition that produces measurable effects on blood flow, pressure gradients, or organ perfusion sufficient to cause clinical symptoms or physiological compromise. In aortic surgery, this term is used to characterize stenoses, aneurysms, or other pathology that warrant intervention based on their impact on cardiovascular function rather than size alone. The determination of hemodynamic significance often involves pressure measurements, flow studies, or functional assessments such as stress testing. This concept is crucial for distinguishing between anatomically present disease and clinically relevant pathology requiring treatment.
Usage
Usage note: Always provide supporting evidence (gradients, flow measurements, symptoms) when documenting hemodynamic significance.
In Context
- "The patient had a hemodynamically significant coarctation with a 40 mmHg gradient across the narrowed segment." — Catheterization report
- "While the aneurysm was only 4.8 cm, it was considered hemodynamically significant due to associated aortic regurgitation." — Surgical decision note