Advanced
Technical
IVT
penetrating atherosclerotic ulcer
An atherosclerotic plaque that ulcerates through the internal elastic lamina into the media.
Full Definition
A penetrating atherosclerotic ulcer (PAU) occurs when an atherosclerotic plaque erodes through the internal elastic lamina and penetrates into the medial layer of the aortic wall. This condition is part of the acute aortic syndrome spectrum and typically occurs in elderly patients with extensive atherosclerotic disease. PAUs may lead to intramural hematoma, pseudoaneurysm formation, or frank rupture, and are most commonly found in the descending thoracic and abdominal aorta.
Usage
Usage note: Commonly abbreviated as PAU in clinical notes.
In Context
- "The penetrating atherosclerotic ulcer in the mid-descending thoracic aorta was treated with thoracic endovascular repair." — Operative report
- "Serial imaging showed progression of the penetrating atherosclerotic ulcer with development of a small pseudoaneurysm." — Follow-up imaging report
Also known as
PAU
atherosclerotic ulcer
Don't confuse with
intramural hematoma
aortic dissection