catheter-directed thrombolysis
Also written as: CDT — Catheter-directed thrombolysis
Minimally invasive procedure delivering thrombolytic agents directly into arterial clots via catheter placement.
Full Definition
Catheter-directed thrombolysis (CDT) is an interventional procedure that involves the percutaneous placement of a catheter directly into or adjacent to an arterial thrombus for local delivery of thrombolytic medications. This technique allows for higher local concentrations of fibrinolytic agents while minimizing systemic exposure and associated bleeding risks. The procedure is commonly performed for acute limb ischemia, stroke, and other thrombotic occlusions. Multi-sidehole catheters are typically used to ensure uniform drug distribution throughout the clot. Treatment duration varies but often requires 12-48 hours of continuous infusion with periodic angiographic assessment.
Usage
Usage note: Hyphenate when used as a compound modifier. CDT is the preferred abbreviation in clinical practice.
In Context
- "The patient underwent catheter-directed thrombolysis for acute occlusion of the superficial femoral artery." — Procedure note
- "Catheter-directed thrombolysis was initiated with tissue plasminogen activator at 0.5 mg/hour." — Interventional report