fibromuscular dysplasia
Also written as: FMD — Fibromuscular dysplasia
A non-atherosclerotic vascular disease causing arterial stenosis, most commonly affecting renal and carotid arteries.
Full Definition
Fibromuscular dysplasia (FMD) is a non-inflammatory, non-atherosclerotic arterial disease that primarily affects medium-sized arteries. It is characterized by abnormal cellular proliferation and fibrosis within the arterial wall, leading to stenosis, occlusion, aneurysm, or dissection. The condition most commonly affects the renal arteries (causing renovascular hypertension) and carotid/vertebral arteries, though it can involve other vascular beds. Imaging typically reveals the pathognomonic 'string-of-beads' appearance on angiography.
Usage
Usage note: Often abbreviated as FMD in clinical documentation. Avoid confusing with other causes of arterial stenosis.
In Context
- "The patient's renal angiogram demonstrated the classic string-of-beads appearance consistent with fibromuscular dysplasia." — Radiology report
- "Fibromuscular dysplasia should be considered in young patients presenting with renovascular hypertension." — Clinical assessment note