hemodynamically significant stenosis
Arterial narrowing severe enough to cause measurable reduction in blood flow and pressure gradient.
Full Definition
Hemodynamically significant stenosis refers to arterial narrowing that produces a measurable reduction in blood flow and creates a pressure gradient across the stenotic segment. The threshold for hemodynamic significance varies by vessel location but generally occurs with luminal diameter reduction of 50% or greater, corresponding to approximately 75% cross-sectional area reduction. This level of stenosis begins to affect resting blood flow and becomes more pronounced with increased flow demands. Assessment of hemodynamic significance may involve pressure measurements, flow velocity analysis, or functional testing. Recognition of hemodynamically significant stenosis is crucial for determining the need for intervention and predicting clinical outcomes.
Usage
Usage note: Distinguish from purely anatomic measurements; emphasizes functional impact on blood flow.
In Context
- "The 80% stenosis was deemed hemodynamically significant based on the measured pressure gradient." — Cardiac catheterization report
- "Despite moderate anatomic narrowing, the lesion was not hemodynamically significant under resting conditions." — Physiologic assessment report