plaque morphology
Detailed characterization of atherosclerotic plaque composition, surface characteristics, and structural features that influence rupture risk.
Full Definition
Plaque morphology encompasses the detailed assessment of atherosclerotic plaque characteristics including composition, surface features, structural integrity, and vulnerability markers. Key morphological features include plaque surface (smooth, irregular, or ulcerated), echogenicity (echogenic, echolucent, or heterogeneous), calcification patterns, and presence of necrotic cores or fibrous caps. Advanced imaging techniques can identify high-risk plaque features such as thin fibrous caps, large lipid cores, intraplaque hemorrhage, and inflammatory infiltrates, which correlate with increased risk of plaque rupture and thromboembolic events.
Usage
Usage note: Distinguish between morphological features (structure) and compositional features (material content).
In Context
- "Advanced plaque morphology analysis revealed a heterogeneous plaque with ulcerated surface features." — Detailed imaging report
- "The unstable plaque morphology warranted aggressive medical therapy to prevent rupture." — Clinical management plan