Gonadotropin
Pronunciation: goh-nad-oh-TROE-pin
Hormones that stimulate the gonads, including FSH, LH, and hCG, used therapeutically in ovulation induction protocols.
Full Definition
Gonadotropins are glycoprotein hormones essential for reproductive function, naturally produced by the anterior pituitary gland and placenta. In ART, synthetic and purified gonadotropins are used for controlled ovarian stimulation to develop multiple follicles simultaneously. The main therapeutic gonadotropins include follicle-stimulating hormone (FSH) for follicular development, luteinizing hormone (LH) for final oocyte maturation, and human chorionic gonadotropin (hCG) for ovulation triggering. These medications are administered via subcutaneous injection and require careful monitoring through ultrasound and hormone level assessment. Dosing protocols are individualized based on patient age, ovarian reserve, and previous response patterns.
Usage
Usage note: Singular form ends in -in; plural adds -s. Distinguish from gonadotropin-releasing hormone (GnRH).
In Context
- "Daily gonadotropin injections were initiated on cycle day 2 following baseline ultrasound confirmation." — Treatment protocol documentation
- "The patient's response to gonadotropin stimulation exceeded expectations with 18 mature follicles identified." — Monitoring visit notes