Professional
Technical
IVT
Inner Cell Mass
Also written as: ICM — Inner Cell Mass
The cluster of cells within a blastocyst that will develop into the fetus.
Full Definition
The inner cell mass (ICM) is a group of pluripotent cells located within the blastocyst cavity that gives rise to the fetus proper. During blastocyst formation, cells differentiate into either trophectoderm (future placenta) or inner cell mass (future fetus). ICM quality is assessed during embryo grading and significantly influences implantation potential and pregnancy outcomes. A well-defined, cohesive ICM indicates higher developmental competence and better prognosis for successful pregnancy.
In Context
- "The blastocyst exhibited an excellent inner cell mass with tight, cohesive cells." — Embryology report
- "Inner cell mass quality was graded as 'A' indicating optimal developmental potential." — Embryo assessment
Also known as
ICM
embryoblast
Contrasted with
trophectoderm
Don't confuse with
blastomeres
trophoblast