Ovarian Hyperstimulation Syndrome
Also written as: OHSS — Ovarian Hyperstimulation Syndrome
A potentially serious complication of fertility treatments involving ovarian enlargement and fluid retention.
Full Definition
Ovarian hyperstimulation syndrome is a systemic disorder that can occur following ovarian stimulation with fertility medications, particularly gonadotropins. OHSS is characterized by enlarged ovaries, increased capillary permeability leading to fluid accumulation in the abdomen and chest, and potential complications including blood clots and kidney dysfunction. The condition ranges from mild to severe, with severe cases requiring hospitalization. Risk factors include young age, polycystic ovary syndrome, and high estradiol levels during stimulation.
Usage
Usage note: Always specify severity level (mild, moderate, severe) when documenting OHSS cases.
In Context
- "The patient developed moderate OHSS requiring cycle cancellation and supportive care." — adverse event report
- "OHSS prevention strategies include GnRH antagonist protocols and elective embryo freezing." — clinical guidelines