Teratospermia
Pronunciation: ter-AH-toe-sper-mee-ah
Abnormal sperm morphology characterized by a high percentage of malformed sperm cells in semen analysis.
Full Definition
Teratospermia refers to a condition where the percentage of morphologically normal sperm falls below the reference threshold, typically less than 4% normal forms according to strict criteria. Morphological abnormalities can affect the sperm head, midpiece, or tail, and may result from genetic factors, environmental toxins, infections, or varicocele. Severe teratospermia significantly impacts natural conception rates and may necessitate ICSI for successful fertilization. Assessment uses strict morphology criteria established by Kruger and colleagues.
Usage
Usage note: One of the three primary sperm parameters; often occurs in combination with other sperm abnormalities.
In Context
- "Semen analysis revealed severe teratospermia with only 1% normal morphology by strict criteria." — Laboratory report
- "The couple was counseled that teratospermia would likely require ICSI for optimal fertilization rates." — Clinical consultation note