ductal carcinoma in situ
Also written as: DCIS
Non-invasive breast cancer confined to the milk ducts without spread to surrounding breast tissue.
Full Definition
Ductal carcinoma in situ (DCIS) is a non-invasive form of breast cancer where abnormal cells are found in the lining of breast ducts but have not spread to surrounding breast tissue. DCIS is considered a precursor to invasive breast cancer and is classified by nuclear grade (low, intermediate, or high) and the presence or absence of necrosis. Treatment typically involves surgical removal with or without radiation therapy. While DCIS itself is not life-threatening, it increases the risk of developing invasive breast cancer. The management approach depends on factors such as size, grade, and patient characteristics.
Usage
Usage note: Always specify 'in situ' to distinguish from invasive ductal carcinoma.
In Context
- "The biopsy revealed high-grade ductal carcinoma in situ with central necrosis." — Pathology report
- "Ductal carcinoma in situ was completely excised with clear surgical margins." — Surgical pathology report