Professional
Technical
IVT
invasive lobular carcinoma
The second most common type of invasive breast cancer, accounting for 10-15% of cases and often more difficult to detect on imaging.
Full Definition
Invasive lobular carcinoma (ILC) is the second most common form of invasive breast cancer after invasive ductal carcinoma. Unlike ductal carcinoma, lobular cancer grows in a single-file pattern through breast tissue, making it more difficult to detect on mammography and physical examination. ILC tends to be hormone receptor-positive and has a lower likelihood of HER2 overexpression. The growth pattern can make accurate size assessment challenging, and patients may require MRI for proper staging.
Usage
Usage note: Always specify 'invasive' to distinguish from lobular carcinoma in situ (LCIS).
In Context
- "The pathology report confirmed invasive lobular carcinoma with lobular growth pattern extending beyond the tumor bed." — Pathology report
- "MRI is often recommended for patients with invasive lobular carcinoma due to the tumor's tendency to grow in a single-file pattern." — Clinical protocol
Also known as
ILC
lobular carcinoma
Contrasted with
invasive ductal carcinoma
ductal carcinoma in situ
Don't confuse with
invasive ductal carcinoma
lobular carcinoma in situ