Intermediate
Technical
IVT
biomarker-driven therapy
Treatment selection based on specific molecular characteristics of a patient's tumor.
Full Definition
Biomarker-driven therapy refers to the selection of cancer treatments based on specific molecular, genetic, or protein biomarkers present in a patient's tumor rather than solely on tumor histology or location. This precision medicine approach matches patients to therapies most likely to benefit them based on tumor biology. Biomarker-driven strategies have improved outcomes across many cancer types and require comprehensive molecular testing, multidisciplinary interpretation, and integration of genomic data into clinical decision-making processes.
Usage
Usage note: Hyphenate biomarker-driven therapy; emphasize the biomarker-based selection process.
In Context
- "The oncology team implemented biomarker-driven therapy selection resulting in improved response rates." — Quality improvement report
- "Biomarker-driven therapy requires comprehensive genomic profiling and molecular tumor board review." — Clinical pathway document
Also known as
precision therapy
biomarker-guided treatment
molecularly targeted therapy
Contrasted with
empirical therapy
histology-based treatment
Don't confuse with
targeted therapy
personalized medicine
genomic medicine