lymphadenopathy
Pronunciation: /lɪmˌfædəˈnɒpəθi/
Abnormal enlargement of lymph nodes that may indicate infection, autoimmune disease, or malignancy including lymphoma or metastatic cancer.
Full Definition
Lymphadenopathy refers to the pathological enlargement of lymph nodes beyond normal size limits, typically greater than 1 cm in most anatomical regions. In cancer biology, lymphadenopathy can result from primary lymphoid malignancies such as lymphoma or leukemia, or from metastatic spread of solid tumors to regional lymph nodes. The pattern, size, consistency, and location of enlarged lymph nodes provide important diagnostic clues. Lymphadenopathy assessment often requires imaging studies, laboratory tests, and potentially lymph node biopsy for definitive diagnosis.
Usage
Usage note: Specific anatomical descriptors should be included (e.g., cervical lymphadenopathy, mediastinal lymphadenopathy).
In Context
- "Imaging revealed extensive mediastinal lymphadenopathy suggestive of lymphoma." — Radiology report
- "The patient presented with painless cervical lymphadenopathy requiring further evaluation." — Clinical assessment