sentinel lymph node biopsy
Also written as: SLNB — Sentinel Lymph Node Biopsy
A surgical procedure to identify and remove the first lymph node(s) that cancer cells are most likely to spread to from a primary tumor.
Full Definition
Sentinel lymph node biopsy (SLNB) is a minimally invasive surgical technique used to determine whether cancer has spread to the regional lymph nodes. The procedure involves injecting a radioactive tracer and/or blue dye near the primary tumor, then identifying and removing the first one to three lymph nodes that drain the tumor area. If the sentinel nodes are negative for cancer, it is highly likely that the remaining lymph nodes are also cancer-free, potentially avoiding the need for complete lymph node dissection and its associated morbidity.
Usage
Usage note: Specify the anatomical region when documenting (e.g., axillary SLNB, groin SLNB).
In Context
- "Sentinel lymph node biopsy identified two nodes, both negative for metastatic disease on frozen section analysis." — Operative report
- "The patient was not a candidate for sentinel lymph node biopsy due to previous axillary surgery and altered lymphatic drainage." — Surgical consultation note