tumor grade
A pathological assessment of how abnormal cancer cells appear under microscopy compared to normal cells.
Full Definition
Tumor grade is a histopathological classification system that describes the degree of cellular abnormality and differentiation in cancer tissue. Grading systems vary by cancer type but generally range from low-grade (well-differentiated, slow-growing) to high-grade (poorly differentiated, aggressive). The grade helps predict tumor behavior and inform treatment decisions, with higher grades typically indicating more aggressive cancers requiring intensive therapy.
Usage
Usage note: Often confused with tumor stage; grade refers to cellular appearance while stage refers to extent of spread.
In Context
- "The pathology report indicated a high tumor grade, suggesting aggressive disease requiring immediate intervention." — Medical record
- "Tumor grade and stage are distinct but complementary prognostic factors in cancer care." — Clinical guideline