COSMIC
Also written as: COSMIC — Catalogue Of Somatic Mutations In Cancer
The Catalogue Of Somatic Mutations In Cancer database, a reference resource for cancer genomic variants.
Full Definition
COSMIC (Catalog Of Somatic Mutations In Cancer) is a comprehensive database that catalogs somatic mutations found in human cancers. It serves as a critical reference for cancer genomics research and clinical interpretation of variants. The database contains detailed information about mutations, their frequencies across different cancer types, and associated clinical data. Editors working with cancer genomics reports must understand COSMIC's role as the primary reference for variant interpretation and ensure proper citation formatting when referencing COSMIC identifiers.
Usage
Usage note: Always capitalize as COSMIC, not Cosmic. Include version number when citing specific database releases.
In Context
- "The variant was cross-referenced against the COSMIC database to determine its prevalence in colorectal adenocarcinomas." — genomic testing report
- "COSMIC ID: COSV12345678 was cited for this recurrent mutation in lung cancer patients." — molecular pathology report