DCIS
Pronunciation: DEE-sis
Also written as: DCIS — ductal carcinoma in situ
Ductal carcinoma in situ; abnormal cells confined to breast milk ducts without invasion into surrounding tissue.
Full Definition
Ductal carcinoma in situ represents a non-invasive breast cancer where abnormal cells are present within the milk ducts but have not spread to nearby breast tissue. Often detected through mammographic screening as microcalcifications, DCIS is considered a precancerous condition or stage 0 breast cancer. Treatment typically involves surgery, and the condition carries an excellent prognosis when properly managed. The detection of DCIS through screening programs is both a benefit (preventing progression to invasive cancer) and a source of debate regarding potential overtreatment.
Usage
Usage note: Typically written in all caps as an acronym; spell out on first use in patient-facing materials.
In Context
- "The pathology report confirmed high-grade DCIS with comedo necrosis spanning 2.5 cm." — Pathology report
- "Screening mammography has led to increased detection of DCIS, raising questions about optimal management strategies." — Clinical review article