sessile serrated polyp
Also written as: SSP
Type of colorectal polyp with serrated architecture and malignant potential requiring specific surveillance intervals.
Full Definition
Sessile serrated polyps are a distinct type of colorectal polyp characterized by a serrated histologic pattern and flat or sessile morphology. Unlike traditional adenomatous polyps, SSPs follow an alternative pathway to colorectal cancer through BRAF mutations and CpG island methylator phenotype. These lesions are often difficult to detect endoscopically due to their subtle appearance and are associated with interval cancers. SSPs require specific surveillance recommendations that differ from conventional adenoma follow-up protocols.
Usage
Usage note: Distinguish clearly from hyperplastic polyps and traditional serrated adenomas in clinical documentation.
In Context
- "The pathology report identified a 12mm sessile serrated polyp in the ascending colon." — Colonoscopy report
- "Sessile serrated polyps larger than 10mm require surveillance colonoscopy in 3 years." — Surveillance guideline