ACT
Also written as: ACT — activated clotting time
Activated clotting time, a point-of-care test measuring blood coagulation status during cardiac surgery requiring anticoagulation.
Full Definition
Activated clotting time (ACT) is a bedside coagulation test essential for monitoring anticoagulation during cardiac surgery, particularly when cardiopulmonary bypass is employed. The test measures how long blood takes to clot after activation with a standardized activator, typically kaolin or celite. Target ACT values usually exceed 400-480 seconds during CPB to prevent clot formation in the bypass circuit. The test is performed frequently throughout surgery, with heparin dosing adjusted based on ACT results. ACT monitoring is crucial for patient safety, as inadequate anticoagulation can lead to thrombotic complications, while excessive anticoagulation increases bleeding risk.
Usage
Usage note: Use all caps for the abbreviation; always specify target values in institutional protocols.
In Context
- "The ACT was 520 seconds following heparin administration, confirming adequate anticoagulation for bypass." — anesthesia record
- "Serial ACT measurements were obtained every 30 minutes during the procedure." — perfusion record