modified ultrafiltration
Also written as: MUF — modified ultrafiltration
A blood concentration technique performed after separation from cardiopulmonary bypass to remove excess fluid.
Full Definition
Modified ultrafiltration is a technique used after separation from cardiopulmonary bypass to concentrate the patient's blood by removing excess fluid and inflammatory mediators. Unlike conventional ultrafiltration performed during bypass, modified ultrafiltration occurs after bypass using arterial and venous cannulas already in place. The process involves circulating the patient's blood through a hemofilter to remove plasma water while returning concentrated blood cells and proteins. This technique helps reduce edema, improve hematocrit, remove inflammatory cytokines, and may improve postoperative cardiac and pulmonary function, particularly in pediatric patients.
Usage
Usage note: Commonly abbreviated as MUF, particularly in pediatric cardiac surgery.
In Context
- "Modified ultrafiltration was performed for 15 minutes after bypass separation." — perfusion record
- "The patient's hematocrit increased from 22% to 28% following modified ultrafiltration." — operative note