SPECT
Pronunciation: spekt
Also written as: SPECT — single-photon emission computed tomography
A nuclear imaging technique that creates three-dimensional images of myocardial perfusion using radioactive tracers.
Full Definition
Single-photon emission computed tomography (SPECT) is a nuclear cardiology imaging modality that uses gamma-emitting radiopharmaceuticals to assess myocardial perfusion and viability. The technique involves injecting tracers such as technetium-99m sestamibi or thallium-201, which are taken up by viable myocardial cells in proportion to blood flow. SPECT imaging is typically performed at rest and during pharmacological or exercise stress to detect coronary artery disease. The resulting tomographic images allow for precise localization of perfusion defects and assessment of their extent and severity, making SPECT valuable for diagnosing coronary disease and evaluating treatment response.
Usage
Usage note: Pronounced as a word, not spelled out letter by letter.
In Context
- "The SPECT study demonstrated a large reversible perfusion defect in the inferior wall." — Nuclear cardiology report
- "Pharmacological stress SPECT imaging is preferred in patients unable to exercise adequately." — Imaging protocol document