de novo aortic stenosis
Pronunciation: deh NO-vo
Newly developed aortic valve stenosis in previously normal valve, distinct from progression of existing disease.
Full Definition
De novo aortic stenosis refers to the development of aortic valve stenosis in a valve that was previously normal or showed only minimal abnormalities on prior examinations. This condition is distinguished from the progression of pre-existing aortic stenosis and typically represents rapid calcific degeneration. The term is particularly relevant in surgical planning and risk assessment, as the etiology and rate of progression may influence treatment decisions and timing of intervention.
Usage
Usage note: Italicize 'de novo' as it is a Latin phrase; distinguish from progression of existing disease.
In Context
- "The patient developed de novo aortic stenosis over an 18-month period without prior valve disease." — Clinical assessment
- "Serial echocardiograms documented de novo aortic stenosis in a previously normal tricuspid valve." — Follow-up documentation