transmural myocardial infarction
Full-thickness death of heart muscle extending from endocardium to epicardium, often requiring surgical intervention.
Full Definition
A transmural myocardial infarction involves necrosis of the entire thickness of the myocardial wall, extending from the inner endocardial surface to the outer epicardial surface. This type of infarction typically results from complete occlusion of a coronary artery and is associated with Q-wave formation on electrocardiography. Patients may require emergency surgical revascularization, and complications can include mechanical defects such as ventricular septal rupture or papillary muscle rupture requiring immediate surgical repair.
Usage
Usage note: Distinguish clearly from non-transmural or subendocardial infarctions in clinical documentation.
In Context
- "The patient suffered a transmural myocardial infarction requiring emergency surgical revascularization." — Emergency documentation
- "Pathology confirmed transmural myocardial infarction with evidence of papillary muscle rupture." — Autopsy report