diastolic dysfunction
Impaired relaxation and filling of the left ventricle during diastole, often with preserved systolic function.
Full Definition
Diastolic dysfunction refers to abnormal left ventricular relaxation, filling, or distensibility that occurs during diastole (the heart's relaxation phase). Unlike systolic dysfunction where the heart's pumping ability is compromised, diastolic dysfunction primarily affects the heart's ability to fill with blood between beats. This condition is commonly associated with heart failure with preserved ejection fraction (HFpEF) and can result from conditions such as hypertension, diabetes, or aging. Diagnosis typically involves echocardiographic assessment of mitral inflow patterns and tissue Doppler imaging.
Usage
Usage note: Often contrasted with systolic dysfunction; important to specify grade when documented.
In Context
- "Echocardiography revealed grade II diastolic dysfunction with elevated left atrial pressure." — diagnostic report
- "The patient's symptoms were attributed to diastolic dysfunction despite normal ejection fraction." — clinical assessment