fractional flow reserve
Also written as: FFR — fractional flow reserve
Invasive measurement of the functional significance of coronary stenosis using pressure wire assessment.
Full Definition
Fractional flow reserve (FFR) is a physiological measurement that determines the functional significance of coronary artery stenoses during cardiac catheterization. FFR is calculated as the ratio of distal coronary pressure to aortic pressure during maximal hyperemia, typically induced with adenosine. An FFR value of 0.80 or less indicates hemodynamically significant stenosis that would benefit from revascularization. This technique helps guide treatment decisions by distinguishing between anatomically significant but functionally insignificant lesions and those that truly limit coronary blood flow. FFR-guided percutaneous coronary intervention has been shown to improve outcomes compared to angiography-guided procedures alone.
Usage
Usage note: Commonly abbreviated as FFR; always include the specific numeric value and threshold interpretation.
In Context
- "Fractional flow reserve measurement revealed an FFR of 0.75, confirming hemodynamic significance of the lesion." — cardiac catheterization report
- "The decision to proceed with stenting was based on fractional flow reserve rather than angiographic appearance alone." — interventional procedure note