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Professional Technical In the Industry Vocabulary Test

heart failure with preserved ejection fraction

Also written as: HFpEF — heart failure with preserved ejection fraction

A type of heart failure where the heart's pumping function appears normal but filling is impaired, also known as diastolic heart failure.

Full Definition

Heart failure with preserved ejection fraction (HFpEF) is a clinical syndrome characterized by symptoms and signs of heart failure in the presence of a normal or near-normal left ventricular ejection fraction (typically ≥50%). Previously termed diastolic heart failure, HFpEF results from impaired ventricular relaxation and increased filling pressures rather than reduced contractility. The condition is increasingly common, particularly in elderly patients with hypertension, diabetes, and obesity. Diagnosis requires evidence of elevated filling pressures through echocardiography, cardiac catheterization, or elevated natriuretic peptides, as standard imaging may appear deceptively normal.

Usage

Usage note: Prefer 'HFpEF' over outdated 'diastolic heart failure' in contemporary documentation.

In Context

  • "The patient's symptoms were consistent with heart failure with preserved ejection fraction, confirmed by elevated BNP and diastolic dysfunction on echo." — Cardiology consultation
  • "Treatment of HFpEF focuses on symptom management and treating underlying comorbidities." — Heart failure clinic note

Also known as

HFpEF diastolic heart failure

Contrasted with

HFrEF heart failure with reduced ejection fraction systolic heart failure

Don't confuse with

heart failure with reduced ejection fraction heart failure with mid-range ejection fraction

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