coagulopathy
Pronunciation: koh-ag-yoo-LOP-ah-thee
Abnormal blood clotting function commonly seen after cardiopulmonary bypass.
Full Definition
Coagulopathy refers to any disorder affecting the blood's ability to clot properly, frequently occurring after cardiac surgery with cardiopulmonary bypass. This condition results from multiple factors including hemodilution, platelet dysfunction, consumption of clotting factors, and fibrinolysis activation. Post-bypass coagulopathy requires prompt recognition and management with blood products, antifibrinolytics, or factor concentrates to prevent excessive bleeding.
Usage
Usage note: Distinguish from specific bleeding disorders; describe underlying cause when possible
In Context
- "Post-operative coagulopathy was treated with fresh frozen plasma and platelet transfusion." — Post-operative care plan