myocardial oxygen consumption
Also written as: MVO2 — myocardial oxygen consumption
The rate of oxygen utilization by cardiac muscle, primarily determined by heart rate, contractility, and wall tension.
Full Definition
A physiologic parameter representing the amount of oxygen consumed by the myocardium per unit time, typically expressed as mL O2/min/100g of heart muscle. MVO2 is determined by three primary factors: heart rate, myocardial contractility, and ventricular wall tension (influenced by preload and afterload). Additional minor determinants include basal metabolism and activation energy for contraction. In cardiac anesthesia, understanding MVO2 is crucial for myocardial protection strategies, as interventions that reduce oxygen demand (beta-blockade, hypothermia) or improve supply (coronary revascularization) can prevent ischemia during periods of stress or reduced coronary flow.
Usage
Usage note: Commonly abbreviated as MVO2; distinguish from myocardial oxygen delivery (MDO2) in clinical discussions.
In Context
- "Beta-blockade was used to reduce myocardial oxygen consumption during the high-risk period before bypass initiation." — Anesthesia plan
- "The anesthesiologist monitored indicators of myocardial oxygen consumption including rate-pressure product throughout the procedure." — Intraoperative note