pump prime
Solution used to fill the cardiopulmonary bypass circuit before initiating extracorporeal circulation.
Full Definition
Pump prime refers to the crystalloid or colloid solution used to fill the cardiopulmonary bypass circuit, oxygenator, and tubing before connecting the patient to extracorporeal circulation. The prime typically consists of balanced crystalloid solutions, albumin, mannitol, heparin, and sometimes blood products, depending on patient factors and institutional protocols. The volume and composition of the prime significantly affect the patient's hematocrit, electrolyte balance, and oncotic pressure during bypass. Modern techniques focus on minimizing prime volume to reduce hemodilution, particularly in small patients or those with limited physiologic reserve.
Usage
Usage note: Can be used as both a noun and verb; 'to prime the pump' means to fill the circuit.
In Context
- "The pump prime consisted of lactated Ringer's solution with albumin and mannitol to minimize hemodilution." — Perfusion record
- "A blood prime was used to maintain the patient's hematocrit above 20% during cardiopulmonary bypass." — Operative report