coagulopathy
Abnormal blood clotting function commonly occurring during cardiac surgery due to multiple factors including cardiopulmonary bypass effects.
Full Definition
Coagulopathy in cardiac surgery results from multiple factors including hemodilution, hypothermia, platelet dysfunction from cardiopulmonary bypass, consumption of clotting factors, and effects of anticoagulation. This condition manifests as prolonged bleeding times, abnormal laboratory values, and increased postoperative bleeding. Management involves targeted therapy based on point-of-care testing such as thromboelastography, including platelet transfusion, fresh frozen plasma, cryoprecipitate, or specific factor concentrates. Prevention strategies include minimizing bypass time and maintaining normothermia.
Usage
Usage note: Specify whether acquired (surgical) or inherited coagulopathy when relevant.
In Context
- "Post-bypass coagulopathy required platelet transfusion and fresh frozen plasma." — Operative report
- "TEG analysis revealed coagulopathy with poor clot strength necessitating factor replacement." — Anesthesia record