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Intermediate Technical In the Industry Vocabulary Test

DAPT

Also written as: DAPT — Dual Antiplatelet Therapy

Dual Antiplatelet Therapy combining aspirin with a P2Y12 inhibitor for prevention of thrombotic events after acute coronary syndromes or PCI.

Full Definition

Dual Antiplatelet Therapy (DAPT) is the standard of care combination of aspirin plus a P2Y12 receptor antagonist (clopidogrel, prasugrel, or ticagrelor) used to prevent thrombotic events in patients with acute coronary syndromes or following percutaneous coronary intervention. The regimen typically involves low-dose aspirin (75-100mg daily) combined with a more potent P2Y12 inhibitor for a specified duration ranging from one month to several years, depending on bleeding and thrombotic risk assessment. The optimal duration requires balancing ischemic protection against bleeding risk.

Usage

Usage note: Specify both agents and duration; distinguish from triple therapy which adds oral anticoagulation.

In Context

  • "The patient was discharged on DAPT with aspirin 81mg and ticagrelor 90mg twice daily for 12 months post-stenting." — Discharge medication reconciliation
  • "DAPT duration should be individualized based on bleeding and ischemic risk scores." — Clinical practice guideline

Also known as

dual antiplatelet therapy combination antiplatelet therapy

Contrasted with

single antiplatelet therapy anticoagulation monotherapy

Don't confuse with

triple therapy oral anticoagulation single antiplatelet therapy
culprit vessel ← Back to glossary diastolic

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