heart failure with preserved ejection fraction
Heart failure syndrome with normal or near-normal left ventricular systolic function.
Full Definition
Heart failure with preserved ejection fraction (HFpEF) is a clinical syndrome characterized by symptoms and signs of heart failure despite maintained left ventricular ejection fraction (typically ≥50%). Previously called diastolic heart failure, HFpEF involves impaired ventricular relaxation and increased filling pressures. It commonly affects elderly patients, particularly women, and is associated with hypertension, diabetes, and obesity. Diagnosis can be challenging as it requires demonstration of elevated filling pressures along with typical heart failure symptoms. Treatment focuses on managing comorbidities and symptom relief, as specific therapies proven to improve outcomes are limited.
Usage
Usage note: HFpEF is preferred over 'diastolic heart failure' in current terminology.
In Context
- "The patient's presentation was consistent with heart failure with preserved ejection fraction based on echocardiographic findings." — Cardiology consultation
- "Management of heart failure with preserved ejection fraction focuses primarily on blood pressure control and diuretic therapy." — Treatment protocol