papillary fibroelastoma
Benign cardiac tumor with characteristic frond-like projections, most commonly affecting cardiac valves and associated with embolic risk.
Full Definition
Papillary fibroelastoma is the most common primary cardiac tumor affecting valves, characterized by multiple delicate, frond-like projections arising from the valve surface. These tumors consist of a central core of loose connective tissue covered by endothelium, creating a sea anemone-like appearance. They most commonly affect the aortic valve, followed by mitral, tricuspid, and pulmonary valves. While histologically benign, these tumors pose significant embolic risk due to their friable nature and tendency to fragment. The condition typically affects older adults and may present with stroke, transient ischemic attacks, or other embolic phenomena. Echocardiography shows characteristic mobile, stippled masses attached to valve surfaces.
Usage
Usage note: Most common primary valvular tumor; high embolic risk despite benign histology.
In Context
- "Echocardiography revealed a mobile papillary fibroelastoma on the aortic valve with high embolic potential." — Cardiology consultation
- "The excised valve lesion showed classic papillary fibroelastoma with frond-like projections and endothelial covering." — Surgical pathology report