ACE inhibitor
Also written as: ACE — Angiotensin-Converting Enzyme Inhibitor
Antihypertensive medication class blocking angiotensin-converting enzyme, with cardiovascular and renal protective benefits.
Full Definition
A class of medications that inhibit angiotensin-converting enzyme, preventing the conversion of angiotensin I to angiotensin II, thereby reducing blood pressure and providing cardiovascular protection. ACE inhibitors (such as lisinopril, enalapril, ramipril) are first-line antihypertensive agents, particularly beneficial in patients with diabetes, heart failure, or chronic kidney disease. These medications offer organ protection beyond blood pressure reduction, including reduction in cardiovascular events and progression of diabetic nephropathy.
Usage
Usage note: Always capitalize ACE; distinguish from ARBs which have similar effects but different mechanisms.
In Context
- "ACE inhibitor therapy was initiated for both hypertension control and cardiovascular protection." — Treatment plan
- "The patient developed a dry cough, a known side effect of ACE inhibitors." — Adverse reaction report