beta-blocker
A class of medications that block beta-adrenergic receptors, used for blood pressure control and post-MI cardioprotection.
Full Definition
Beta-blockers are medications that selectively block beta-adrenergic receptors, reducing heart rate, blood pressure, and myocardial oxygen demand. In cardiovascular prevention, they are used for hypertension management and are particularly important in secondary prevention following myocardial infarction, where they reduce mortality and recurrent events. Common beta-blockers include metoprolol, carvedilol, and atenolol. Cardioselective beta-blockers (beta-1 selective) are preferred in patients with asthma or COPD. Beta-blockers with additional alpha-blocking properties (like carvedilol) may provide additional benefits in heart failure patients.
Usage
Usage note: Always hyphenate. Specify selectivity (cardioselective vs non-selective) when clinically relevant.
In Context
- "Beta-blocker therapy was optimized to achieve target heart rate below 60 bpm." — Medication titration
- "The patient tolerated the beta-blocker well with no bronchospasm." — Safety assessment