DAPT
Also written as: DAPT — dual antiplatelet therapy
Dual antiplatelet therapy combining aspirin with a P2Y12 inhibitor, used after acute coronary syndromes or PCI.
Full Definition
Dual antiplatelet therapy (DAPT) refers to the combination of aspirin with a P2Y12 receptor inhibitor such as clopidogrel, prasugrel, or ticagrelor. DAPT is the standard of care following acute coronary syndromes and percutaneous coronary intervention to prevent stent thrombosis and recurrent ischemic events. The duration of DAPT varies based on clinical presentation, stent type, and bleeding risk, typically ranging from 6-12 months but potentially longer in high-risk patients. The choice of P2Y12 inhibitor and DAPT duration requires balancing ischemic and bleeding risks using validated risk scores.
Usage
Usage note: Use all caps for acronym. Always specify the specific agents used in DAPT regimen.
In Context
- "DAPT with aspirin and clopidogrel was continued for 12 months post-STEMI." — Treatment protocol
- "The DAPT score suggested extended therapy beyond 12 months in this high-risk patient." — Risk assessment